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Search Results for " nmda receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T40999 NMDA receptor antagonist 2
NMDA receptor antagonist 2 is a highly potent and orally active NR2B subtype-selective antagonist of the N-methyl-D-aspartate (NMDA) receptor. It exhibits remarkable binding affinities, with an IC50 of 1.0 nM and a Ki va...
T60792 NMDA receptor antagonist-3
NMDA receptor antagonist-3 is a NMDA receptor antagonist with a significan recovery rate (40.0%, at 100 μM) and safe toxicological characteristics in SH-SY5Y and human adipose mesenchymal stem cells.
T79374 NMDA receptor antagonist 7 iGluR
Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM. It is potentially useful for research into neurodegenerative diseases [1].
T79375 NMDA receptor antagonist 8 iGluR
Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM. This compound is utilized in research pertaining to neurodegenerative diseases [...
T61924 NMDA receptor modulator 6
NMDA receptor regulator 6 (Compound 183) is an effective NMDA receptor regulator and has research value in neurological disorders.
T63003 NMDA receptor potentiator-1
NMDA receptor potentiator-1 (Compound 1368) is a subunit-selective NMDA receptor enhancer with IC50 values of 4 μM and 5 μM for NR2C and NR2D expression, respectively.
T61470 NMDA receptor antagonist 5
NMDA receptor antagonist 5 (Compound 10e), a potent and non-toxic NMDA receptor antagonist, exhibits brain permeability. It is of significance in studying neurological disorders [1].
T60685 NMDA receptor modulator 3
NMDA receptor modulator 3 (Compound 99) is a potent modulator of NMDA receptor that can be used in the research of neurological disorder [1].
T79273 NMDA receptor antagonist 6 iGluR
NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective efficacy. It safeguards PC12 cells from NMDA-induced damage and a...
T61117 NMDA receptor modulator 5
NMDA receptor modulator 5 (Compound 195), a potent NMDA receptor modulator, exhibits potential for neurological disorder research [1].
T60552 NMDA receptor modulator 2
NMDA receptor modulator 2 (Compound 1) is a potent modulator of the NMDA receptor that can be used for neurological disorder research [1].
T60960 NMDA receptor modulator 4
NMDA receptor modulator 4 (Compound 169) can be used for the research of neurological disorder that is a potent modulator of NMDA receptor [1].
T60306 NMDA receptor antagonist 4
NMDA receptor antagonist 4 (IIc) is an uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC 50 of 1.93 μM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability...
T4979 Procyclidine hydrochloride (±)-Procyclidine hydrochlorid NMDAR , iGluR
Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.
T9157 GP130 receptor agonist-1 N-(4-Fluorophenyl)-4-phenyl-2-thiazolami Interleukin
GP130 receptor agonist-1 (N-(4-Fluorophenyl)-4-phenyl-2-thiazolami) is a potent, brain-penetrant and orally active GP130 receptor agonist.
T6134 IEM 1754 2HBr IEM 1754 dihydrobromide GluR
IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
T16286 Nelonemdaz Neu2000 Topoisomerase
Neu2000 is an uncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor.
T23449 TCS 46b NMDAR
NR1A/NR2B NMDA receptor antagonist,orally active
T1186L Ifenprodil RC 61-91,RC-61-91,RC61-91,RC 6191 Adrenergic Receptor , NMDAR
Ifenprodil (RC61-91) is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, Ifenprodil inhibit...
T27178 Dimiracetam ISF4185,ISF-4185,NT11624,NT-11624,BND11624,BND-11624
Dimiracetam, a NMDA-receptor antagonist, is used potentially for the treatment of neuropathic pain.
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TargetMol